Gunther Enderlein (1872-1968) is often called the founder of Isopathic Medicine, though the work of Johan Joseph Wilhelm Lux and Antoine Bechamp does proceed it. Enderlein was a German zoologist and entomologist and built his research on Antoine Bechamp’s discoveries that unfavorable host and environmental conditions destabilize the host’s native microzymas. Enderlein proved that blood is not sterile, and that a microorganism can appear in various developmental stages and in diverse forms, without the loss of its specific characteristics. He came to the conclusion that the monomorphistic perspective of disease conditions favored by Louis Pasteur and others could no longer be maintained and that a pleomorphic perspective more accurately reflected the disease process.

Pleomorphic remedies(also known as Isopathy/ Sanum Remedies) are a form of oral therapy that rests on the belief in the fundamental mutability of form in microorganisms and that microorganisms can abruptly change from an avirulent benign form into a potentially virulent, pathogenic form. Pleomorphism proposes that an endobiont (symbiotic, primal plant germ in the erythrocyte, as named by Professor Dr. Gunther Enderlein) lives in genuine symbiosis with the host organism (the patient) with mutual benefits. Only through outer factors can the endobiont multiply and develop in a process which can considerably disturb the symbiotic equilibrium and cause dysfunction in the body. 

More simply, Pleomorphism is based on the theory that every warm-blooded organism houses a primal plant germ, which can change in form through environmental influences. In the interest of comparison, allopathic medicine (western medicine) rests on monomorphism which assigns only a single form and function to microorganisms and does not recognize cyclic developmental changes.

A lesser known discipline formulated by Johann Joseph Wilhelm Lux in the 1830’s, Isopathy is essentially a more specific subversion of homeopathy. Rather than “like cures like”, isopathy uses “exactly the same thing cures the thing.” Isopathic remedies are made from the actual cause of the illness or from its byproducts, and are not directed against the disease or its symptoms, but instead support the body’s own capabilities for regeneration, whereby genuine healing processes become possible. 

Benefits of Isopathy / Pleomorphic Remedies


Clinical experience has shown that isopathy may be used for a number of conditions and issues, and that the benefits include:

  • Assist in regulating internal ecology (pH and cell respiration) 

  • Regulates dysfunctions of the lymphatic system

  • Supports GI system and its beneficial microflora

  • Supports the elimination of metabolic and decomposition product

  • Reduces the effects of biochemical stress

  • Improves immune function and microcirculation